well it affected the life's in the cities by Manufactured goods cost less in return to the handmade goods which took longer and wasnt as high of quality Fewer good were made by hand
Galileo's work came into conflict with the Church because he proposed that the Earth actually rotates around the Sun, instead of the Earth being the center of the universe, which is what the Church held. It was "resolved" when the Church sentenced him to life in prison. <span />
If i remember correctly he wanted them to "fight back"