In 330 AD, Constantine, then the emperor of the Roman Empire, moved the seat of power to Constantinople. Then, Constantine founded a "second Rome" (the Byzantine Empire). The city was strategically placed on the trade routes between Europe and Asia, and the Mediterranean Sea and the Black Sea, making it ideal for trade and travel.
The Good Neighbor policy was a foreign policy that US President Franklin Roosevelt adopted regarding the affairs of Latin America. Basically it was a non interference and non intervention principle that the US adopted regarding the political and economical affairs to Latin America to show that they were being a "good neighbor." The Good Neighbor allowed the US to build strong ties to several countries in Latin America, however it was essentially dissolves when the Cold War began in 1945 and the US felt a stronger need to protect its close allies.
I would go back to the 1700's to experience Pacific Island of New Britain when it was discovered.