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But the 1920s were an age of extreme contradiction. The unmatched prosperity and cultural advancement was accompanied by intense social unrest and reaction. The same decade that bore witness to urbanism and modernism also introduced the Ku Klux Klan, Prohibition, nativism, and religious fundamentalism.
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In the first years of the Revolutionary War, George Washington and his Continental Army faced a threat that proved deadlier than the British: a smallpox epidemic, lasting from 1775-1782. Infrequent outbreaks and wariness of inoculation made his troops very susceptible to the disease. After heavy losses in Boston and Quebec, Washington implemented the first mass immunization policy in American history.
The technological and industrial history of the United States describes the United States' emergence as one of the most technologically advanced nations in the world. The availability of land and literate labor, the absence of a landed aristocracy, the prestige of entrepreneurship, the diversity of climate and a large easily accessed upscale and literate free market all contributed to America's rapid industrialization. The availability of capital, development by the free market of navigable rivers, and coastal waterways, and the abundance of natural resources facilitated the cheap extraction of energy all contributed to America's rapid industrialization. Fast transport by the very large railroad built in the mid-19th century, and the Interstate Highway System built in the late 20th century, enlarged the markets and reduced shipping and production costs. The legal system facilitated business operations and guaranteed contracts. Cut off from Europe by the embargo and the British blockade in the War of 1812 (1807–15), entrepreneurs opened factories in the Northeast that set the stage for rapid industrialization modeled on British innovations.