Mitochondrion because it’s the powerhouse of the cell.
Human monoclonal antibody (mAbs) are emerging in the field of cancer therapy and have become an increasing proportion of new drugs that are recently approved. Although there are some methods to obtain antigen-specific mAbs from human B cells, it is generally impossible to directly immunize human beings with antigens of interest. For example, for infectious agents, those approaches are largely restricted. To solve these obstacles, two main approaches have been developed; either by humanizing antigen-specific antibodies from small experimental animals (which is laborious due to the great genetic differences from humans) or rely on the in vitro selection of antigen-specific binders from human antibody repertoires. However, the human mAbs developed by these methods are usually with low affinity.
We are now coming up with a much better idea that is humanizing non-human primates mAbs instead of murine mAbs. Due to the close genetic relationship with humans, immunized NHPs have more potential to be isolated with high affinity antibody to human target than other experimental species, such as mouse, rat and rabbit. In addition, with appropriate method, NHP antibodies are much<span> easier to be humanized</span> without any loss of affinity compared to widely used murine antibodies.
Resource: http://www.creative-biolabs.com/High-Affi-TM-Human-Antibody-Discovery.html
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When the organism inherits a mutated gene creating new colored organisms into the population, this can increase diversity. As more organisms inherit the same mutation, the population will become more variated, which can increase the organisms abilities to survive and adapt in a changing environment, and also improve the biological fitness of individuals; resulting in allowing more organisms to reproduce successfully.
Explanation:
Answer:
Since boron only has two electron shells, it is about as capable of gaining electrons as it is of losing electrons, so it behaves as a metalloid. The other elements in this group have more electron shells, so it is much easier for them to lose their valence electrons and they behave like metals.
Ileostomy is a procedure where the end of the small intestine, called the ileum, is brought out of an opening in the belly through surgery. The opening is called a stoma, and its shiny, bright red in color. It is often done after the large intestine has been removed due to cancer or serious physical injuries. Having a stoma, and the need of emptying it several times a day, is disfiguring so the patient often suffer from poor self image. The patient in the case, may be concerned of being unable to continue romantic relationships due to having a stoma. As a nurse, make sure to first make patient understand that ileostomy surgery does not involve the reproductive organs or the gonads. Then, acknowledge that while having a stoma is disfiguring, many organizations are helping increase awareness and acceptance of those who have the condition. Refer the patient to such local stoma advocacy organizations.
