The mass of the star actually determines the stage of the
star after supernova. If the mass of the star is small, then it would become a
very small and dwarf, cold and dead body in space. The mass of the star has to
be less than that of the sun. If the mass of the star is greater than sun, then
it would become a black hole. The mass of the star has to be more than 1.4
times the mass of the sun to become a black hole.
The signs and symptoms of a cluster headache include severe<span> right-sided headache with a runny nose, droopy eyelids, and tearing of the eye on the right side.
</span>The injectable form of sumatriptan<span> (</span>Imitrex<span>), which is commonly used to treat a migraine, is also an effective treatment for acute cluster headache</span>
Biomes, biodiversity, wetlands, permafrost, and estuary
<span>The correct answers are that it lacks cells, DNA, and cannot maintain homeostasis. It doesn't have any organic matter and homeostasis is impossible because it would turn off eventually. It doens't have DNA and it doesn't reproduce. It's just plasma and it is not a living being, it just moves because of the chemical reactions that occur. </span>
Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
