Most important is that it can secrete proteins<span>. </span>Protein<span> is </span>made<span> by rough ER, chemically modified and </span>packaged<span> in the membrane and then vesicles move into the plasma membrane, fuse with it, and then release the contents</span>inside<span>.</span><span>,and budded of from the Golgi, or </span>made<span> by the ER.</span>