somatic hypermutation occurs only in the <u>V or Variable</u> regions of rearranged heavy and light chains.
Somatic hypermutation occurs only in activated B cells, not T cells. This occurs in germinal establishments inside of lymph nodes and the spleen, where B cells are stimulated and T cells are present. Somatic hypermutation is a procedure in which point mutations pile up at rates 106-fold greater than the background mutation rates observed in other genes in the antibody V-regions of both the light and heavy chains.
Somatic hypermutation of immunoglobulin (Ig) genes is important in antibody-mediated immunity. SHM in B cells serves as the molecular foundation for antibody affinity maturation. In this way, SHM plays an important role in optimizing antibody-dependent immune responses.
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Answer:
Primary lymphoid organs: the bone marrow and the thymus
secondary lymphoid organs: adenoids tonsils spleen
the presence of food in the stomach typically causes release of gastrin, but low pH inhibits release of gastrin.
Answer:
B) Prokaryotic DNA is much smaller than eukaryotic DNA.
Explanation:
In biology, one event is correlated with the other event or structure like observed in the DNA. The genetic material of a eukaryote and a prokaryote differ from the other in many ways:
1. The prokaryote possesses only one chromosome which is double-stranded and circular.
2. The eukaryotic organism exhibits more than one chromosome which is not circular.
Since the prokaryotes possess very less amount of DNA then the eukaryotes therefore during DNA replication, the DNA of prokaryote require only one origin of replication from where the replication will start.
Thus, Option-B is correct.
The absense of humans on the island to disturb the biodiversity