A 3-year-old boy is brought to your office by his mother for evaluation of fever loss of appetite and emesis. The symptoms have
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What phenotypic ratio would you expect as a result of a test cross between a dihybrid organism and one that is homozygous recessive for alleles at two independent loci?
a. 3:1
b. 9:3:3:1
c. 1:1:1:1
d. 1:2:1
e. 9:4:2:1
Answer:
c. 1:1:1:1
Explanation:
When a heterozygous individual for two genes is test crossed with a double homozygous recessive individual, the progeny is obtained in 1:1:1:1 phenotypic ratio. This occurs as the heterozygous dominant individual forms four types of gametes in 1:1:1:1 ratio while the homozygous recessive individual would form only one type of gamete having one recessive allele for each gene.
For example, a test cross between TtRr (tall and red) and ttrr (short and white) would produce a progeny in following ratio=
1 tall, red: 1 tall, white: 1 short, red: 1 short, white
Here, T= tall, t= short, R= red, r= white
