Answer and explanation;
-The insulin receptor itself has decreased kinase activity leading to fewer binding sites for singling effectors to become activated.
Therefore; the signaling effectors are less likely to be activated.
-Additionally,, feedback inhibition decreases signaling effector binding to receptor.
-The lack of activation of these initial signaling effectors prevents any subsequent steps from happening.
-We can thus conclude this by saying that higher insulin concentrations are necessary to obtain the same level of signaling leading to physiological effects that would exist in someone without type-2 diabetes.
-Also the requirement for higher insulin concentration means that the cells that respond to insulin are resistant to its effect.
Answer:
joe biden
Explanation:
hes making people lose brain cells every time he talks/stutters
When the continents separated, organisms were forced to be placed in different locations with different environmental conditions. In order to survive in their new environment, over time, various flora and fauna developed various body mechanisms to cope up. This brought up the speciation of flora and fauna.
Explanation:
Aristotle's model shows the planets in the celestial realm moving around the Earth in an orderly manner, in perfect circles and with uniform motion-neither speeding up nor slowing down.
Answer A fabric used to sew the dresses a company sells should be correct. Because renting a factory and fixing something is a Fixed Cost. Let me know if that’s right!