The LHON stands for leber hereditary optic neuropathy is a type of mitochondrial disorder. The disorder is generally observed in young males. The mitochondrial disorder are transferred from mother to its progeny. The disorder causes retinal ganglion cells (RGCs) and the exons of RGCs to degenerate. The disorder causes sudden painless failure of vision. The disorder leads to loss of central vision, optic atropy and central scotoma.
The most of the individuals with LHON do not possess the signs of the disorder. The disorder is caused by mutation in maternal DNA, thus it is a type of mitochondrial disorder.
