The first thing that the farmer should do is formulate a hypothesis in which he will make intelligent guesses on what is happening or develop a theory of which would explain what is happening. It is the first step in scientific investigation in order to formulate questions of why weeds that are sprayed does not die. After this, it is only then the farmer should experiment and after that, he should finalize his findings as it is its conclusion to the problem.
The Marburg virus wasn't mutating this early on, therefore the Coronavirus is much more deadlier and almost impossible to get a cure for, due to the rapid change in pathogens!