Some characteristics of Cinical depression according to the DSM-5 are --Fatigue or loss of energy almost every day -Feelings of worthlessness or guilt almost every day -impaired concentration, indecisiveness -Insomnia or hypersomnia (excessive sleeping) almost every day -Markedly diminished interest or pleasure in almost all activities nearly every day (called anhedonia, this symptom can be indicated by reports from significant others) -Restlessness or feeling slowed down -Recurring thoughts of death or suicide -Significant weight loss or gain (a change of more than 5% of body weight in a month) -related content that is not listed
It's true: Until contagious childhood diseases could be prevented by vaccines, a case of scarlet fever required a sequestration of the invalid for six weeks.