The largest and most important river system in South America is the Amazon. Making A your answer.
Innovations I’m not 100% sure but I do think that’s is right
The most important thing that the designers should take into account are the potential earthquakes - the buildings should be able to withstand the shaking of the ground.
Additionally, Earthquakes often lead to fires, so the buildings should also be fire-proof; especially not made of wood.
Finally, the possibility of a tsunami should be considered.