There are many Dalmatians that have a genetic disease called Hyperuricosuria (Huu). Due to a faulty gene in the DNA of the Dalmatian the uric acid in the body is not broken down by the liver.
The excess amount of uric acid in the blood causes the formation of ammonium urate stones.
Dalmatians affected by Hyperuricosuria have 400-600 mg/24 hours of uric acid in their bodies compared to 10-20 mg/24 hours in other dogs.
<span>The Royal Proclamation had been originally issued by
King George III in 1763 to officially claim British territory in North
America after Britain had won the Seven Years War.</span>
