Hello~
The region that became crossroads for farmers, traders etc is:
D. The Fertile Crescent.
I hope it's correct!
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The person with better evidence and reasoning
In the first major pioneering movement, settlers made their way to Oregon and California by way of the "Oregon Trail", which was also where many settlers would meet with relatives.
An empire is an aggregate of many separate states or territories under a supreme ruler or oligarchy.
And Rome or Italian Roma is a city in and the capital of Italy, in the central part, on the Tiber.
So basically, Rome is also an empire, you can call it the Roman Empire.