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Answer:
The correct answer would be - MMR would be hindered because both strands would be unmethylated and both would appear as new DNA strands and it would not be able to determine which strand has the error
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Explanation:
In gene expression or DNA replication, the enzyme responsible for the synthesis of DNA from nucleoside triphosphate causes errors sometimes such as mismatch base pair that result in a change in genetic makeup.
For MMR, the DNA template and the strand formed required easily to be differentiated. As the newly synthesized strand is unmethylated and the DNA template strand is methylated results in DNA remain hemimethylated for a very short period.
After MMR, DNA adenine methylase enzyme that transfers a methyl group to the adenine of the sequence 5'-GATC-3' daughter strand formed.
Mutated DAM or DNA adenine methylase will not be able to transfer methyl group which leaves both template and daughter strands unmethylated and mismatch repair would be hindered as it will not be able to identify.
This is referred to as the mutual pretense awareness. This is different from the open awareness where the patient, the family, and the health care professionals are aware that the patient is dying and open;y acknowledge that reality. There are four awareness contexts which includes; closed awareness, suspected awareness, mutual pretense awareness and open awareness.
Polio virus is the virus that correctly matches with its structure.The polio virus has a polyhedral shape. The polio virus is considered as the agent that causes poliomyelitis. It is basically a human enterovirus and falls in the family of Picornaviridae. I hope that this answer will come to your help.
