Answer:
Acetylation of histone tails is a reversible process.
DNA is not transcribed when chromatin is packaged tightly in a condensed form.
Methylation of histone tails in chromatin can promote condensation of chromatin.
Acetylation of histone tails in chromatin allows access to DNA for transcription.
Eukaryotic chromatin structure is a highly complex assembly which needs to be simplified in order to undergo process of transcription. Eukaryotic chromatin structure is highly condensed in nature and DNA cannot be access for transcription. Actylation of histone tails is a process in which breaks the bond of attraction between adjacent nucleosomes. It results in chromatin being condensed attains a loose form. Transcription of DNA can occur in a loose chromatin. Methylation can promote condensation or decondensation of chromatin structure depending upon the methyl group present in the histone.
Answer: Option B.
Explanation:
The first experiment of the passage shows that treatment with TGFBR1 and TGFBR2 antagonists led to lower levels of epithelial cell production. For this conclusion to be strongly valid, we want to show a positive correlation between TGFBR activity and epithelial proliferation.
It provides the reader with your topic and give them a central idea of your writing.
