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Zanzabum
3 years ago
11

Albinism in humans is caused by homozygosity for mutant recessive alleles of the tyr gene, which is located on chromosome 11. al

kaptonuria in humans is caused by homozygosity for mutant recessive alleles of the hgd gene, which is located on chromosome 3. suppose that a man and a woman who are each heterozygous carriers of mutant recessive alleles of both the tyr and hgd genes have five children. what is the probability that at least one of their children will have albinsim and/or alkaptonuria?
Biology
2 answers:
yanalaym [24]3 years ago
8 0
Exactly 989527/1048576, or approximately 94.37%  
Since each trait is carried on a different chromosome, the two traits are independent of each other. Since both parents are heterozygous for the trait, each parent can contribute 1 of a possible 4 combinations of the alleles. So there are 16 possible offspring. I'll use "a", "A", "b", "B" to represent each allele and the possible children are aabb, aabB, aaBb, aaBB, aAbb, aAbB, aABb, aABB, Aabb, AabB, AaBb, AaBB, AAbb, AAbB, AABb, and AABB 
Of the above 16 possibilities, there are 7 that are homozygous in an undesired traint and 9 that don't exhibit the undesired trait. So let's first calculate the probability of "what are the chances that all 5 children not exhibiting an undesired trait?" and then subtract that result from 1. So 
1-(9/16)^5 = 1 - 59049/1048576 = 989527/1048576 which is approximately 0.943686485 = 94.3686485%  
So the answer is exactly 989527/1048576, or approximately 94.37%
mel-nik [20]3 years ago
5 0

Answer:

The probability that at least one of their children will have albinsim and/or alkaptonuria is 0.4375

Explanation:

Please look at the solution in the attached Word file.

Download docx
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2. Dominant trait: cleft chin (C) Mother’s gametes: Cc
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.2. Offspring Genotypes will be Cc or cc.

     Offspring phenotypes : Cleft chin or no cleft chin.

    % chance child will have cleft chin: 50%

3.  % chance child will have arched feet: 25%

4.  % chance child will have blonde hair:  50%

5.  % chance child will have normal vision: 25%

 

Explanation:

CASE 1 :

 Dominant trait: cleft chin (C)

    Recessive trait: lacks cleft chin (c)

    Father’s gametes: cc

    Mother’s gametes: Cc

There are two possible combination of Gametes ,

C fom mother and  c from father= Cc

c from mother and c from father = cc

Gametes of Cc Parents=  \frac{1}{2}C + \frac{1}{2} c........(i)

Gametes of cc parents =<u> </u>\frac{1}{2}c + \frac{1}{2}c .........(ii)

Combining (i) and (ii) we get,

\frac{1}{2}  Cc + \frac{1}{2} cc                              

There fore offspring Genotypes will be Cc or cc

Offspring phenotypes :

Genotype Cc then phenotype= Cleft chin

Genotype cc then phenotype = Lacks cleft chin.

percentage chance child will have cleft chin  =\frac{0.5}{1} ×100

Therefore the chance is 50%.

CASE 2 :

Dominant trait: flat feet (A)

Recessive trait: arched feet (a)

Mother’s gametes: Heterozygous (Aa)

Father’s gametes: Heterozygous   (Aa)

There are four possible combination of genotypes are =AA , Aa, Aa and aa

i.e. A from mother, A from father= AA

     A from mother, a from father =Aa

     a from mother, A from Father = Aa

     a from mother, a from father = aa

Gametes of Aa parent =\frac{1}{2} A + \frac{1}{2} a

Gametes of other Aa parent = \frac{1}{2} A + \frac{1}{2} a

                                       <u>..................................................................................</u>

                                              \frac{1}{4} AA + \frac{1}{4} Aa

                                                                           +  \frac{1}{4} Aa +\frac{1}{4} aa

                                   <u>..........................................................................................</u>

                                <u>\frac{1}{4}AA + \frac{1}{2}Aa +\frac{1}{4} aa</u>

Offspring Genotypes will be: AA or Aa or aa

Offsprings phenotype will be:

Genotype AA then phenotype will be Flat feet

Genotype Aa then phenotype will be flat feet

Genotype aa then Phenotype will be arched feet.

Percentage chance child will have arched feet = \frac{0.25}{1} × 100 = 25%

CASE 3:

Dominant trait: Brown hair (B)

Recessive trait: Blonde hair (b)

Mother’s gametes: Homozygous recessive  (bb)

Father’s gametes: Heterozygous  (Bb)

This case is very similar to the case 1 as one parent is homozygous recessive and other parent is heterozygous.

Resulting in  half  Bb and halve bb combination.

Genotypes will be Bb or bb

Phenotypes will be :

Genotype Bb then phenotype Brown hair

Phenotype bb then Phenotype bb.

% chance child will have blonde hair: 50%

CASE 4:

Dominant trait: farsightedness (F)

Recessive trait: normal vision (f)

Mother’s gametes: Heterozygous  (Ff)

Father’s gametes: Heterozygous  (Ff)

This Case is similar to case 2

it will result in one-fourth FF , half Ff and one-fouth ff combination.

Therefore Genotypes will be: FF, Ff and ff

Phenotypes:

Genotype FF  then phenotype farsightedness

Genotype Ff then phenotype  farsightedness

Genotype ff then phenotype normal vision.

% chance child will have normal vision: 25%

 

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DNA (deoxyribonucleic acid) is considered.

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