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dexar [7]
3 years ago
15

Genetic disorders caused by multiple genes interacting with the environment are called

Biology
1 answer:
Elan Coil [88]3 years ago
3 0

Multifactorial disorder

Multifactorial disorders are disorders that involve variations in multiple genes joined with environmental causes. Diseases such as heart disease, type 2 diabetes, and obesity are multifactorial disorder as they do not have single genetic cause but are caused by a combination of environmental factors and life style with mutations in multiple genes.






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In case of a physical support there is a bone system involved, in case of the maintenance of the  body weight there is  wide spectrum of thyroid hormones as well as leptin and ghrelin, according to the recent studies.

Explanation:

There is a whole spectrum of physiological  body systems involved in the maintenance of the body weight in humans, as well as metabolism.  One of the most important hormones are thyroid hormones. According to the most recent studies, the major role there is an adequate function of the digestive system as well. The most important digestive-related hormones are leptin and ghrelin.

In case of the physical protection of the human body weight the major role have bones, cartilages and ligaments. All of the aforementioned structures support the human body organs and other structures. In case of skeleton, it has been estimated that it consists of 206 bones. In case of younger individuals, the human skeleton has a greater protective effect to other body systems. In case of bones, its main role is to have a rigid support for internal organs and other body structures. In that way, the body weight is is supported against the force of gravity. Additonaly, it provides a support for muscles to maintene their movements as ligaments bind to the distal and proximal parts of the corresponding bones. If we analyze the upper parts of skeleton, their promienent role is in the lifting and carrieng objects etc. The lower parts of the skeleton are involved in a variety of functions such as walking, runinng, playing sports etc.

In case of internal portions of skeleton, it is necessary to outline the major role of skeleton for example in the abdominal and peritoneal cavities. In these cases, the role of skeleton is to act protectively to the contained organs in those cavities. In case of bones themselves, they act as aa storage site for diverse minerals (calcium, phosphate etc. ). The bone marrow is a storage site for the production of blood components producing cells.

Thyroid hormones have an essential role in the body weight regulation. Their major role is through the regulation of the energy in the human body. Thyroid impairment (such as hyperthyroidism, hypothyroidism) may have a large impact on the changes in the body weight and basal metabolic rate.

The most important thyroid hormones studied in the context of the body weight regulation are free triiodothyronine (T3), free thyroxine (T4), total T3, total T4 and thyroid stimulating hormone (TSH). Thyroid hormones regulate the basal metabolic rate via increasing ATP production and regulation of the Na⁺/K⁺ and Ca₂⁺ concentrations and gradients.

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