The correct answer is the Influenza Pandemic.
This Influenza (flu) Pandemic killed between 20 and 100 million people (estimates differ) - more than the war itself!
The source of the Pandemic is still not known, and people suggest such places as the US, China and France.
Answer: b. Florida was the first region in the present-day continental United States that Spain colonized.
Explanation:
Florida or Spanish Florida as it was known, was the first territory claimed by a European power in North America.
It was much larger than the present state of Florida and included parts of present day Georgia, Alabama, Mississippi, North Carolina and South Carolina.
Established by Juan Ponce de León for the Spanish crown, Spain found it particularly difficult as well as too unattractive to maintain a significant presence which led to the territory continually shrinking until it's authority in Florida barely extended out of the various ports that were established.
C. Hopefully that is correct.