"Wheat" is the one aspect of the Columbian Exchange among the following choices given in the question that <span>is considered by many to have made possible the European conquest and colonization of the Americas. The correct option among all the options that are given in the question is the first option.</span>
The Sumerians which was an ancient civilization from Mesopotamia were believed to be the first people to make and use a wheel. This invention is vital to many conveniences we have today :)<span />
From what I can see there are multiple correct answers. B and C are both correct. If you can only pick one I'd go with C. More recently businesses have moved more into cities.