Question

When cells are disrupted and fractionated into subcellular components, the enzyme cytochrome p−450 is recovered with the endoplasmic reticulum fraction. Localization of function?

Answer 1

The answer is true-localization of function.

Cytochrome P450 is a family of conserved integral membrane proteins localized primarily in the membrane of the endoplasmic reticulum (ER). These enzymes represent the terminal oxidases in electron transfer chains and their main reaction is the insertion of one atom of oxygen into the aliphatic position of the substrate while the other oxygen atom is reduced to water.