The somatic nervous system I think
When your body develops a tolerance for a medication the body gets used to it being there thus making the medication ineffective.
D. seems the best to me so hope it helps
Answer:
The integumentary system also works closely with the circulatory system and the surface capillaries through your body. Capillaries near the surface of the skin open when your body needs to cool off and close when you need to conserve heat. We can't leave out the important sense of touch.
Integumentary system
-The integumentary system comprises the skin and its appendages acting to protect the body from various kinds of damage, such as loss of water or damages from outside. The integumentary system includes hair, scales, feathers, hooves, and nails.
Circulatory system
-The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.
