Disadvantages of asexual reproduction include: offspring compete for food and space, extreme temperatures can wipe out entire colonies, negative mutations can destroy many offspring.
Water diffuses into the skin via sweat ducts which alters the electrolyte balance. electrolytes can be salts like sodium and potassium. This alters the stability of neurons causing blood vessels to constrict therefore decreasing the amount of fluid in the fingers which would normally give the skin tension. The decrease causes wrinkles.
It should be oxygen because plants take in carbon dioxide, sunlight, and water and get rid of oxygen, energy, and water. (see pic)