A condition in which uncharacteristically large, unusual and immature RBCs known as megaloblasts gets generated by the bone marrow is known as megaloblastic anemia. The condition can arise due to many causes of which deficiencies of folate or vitamin B12 (cobalamin) are the most general ones. The mentioned vitamins perform an essential function in the generation of RBCs.
The signs and symptoms of megaloblastic anemia are lightheadedness, shortness of breath, pale skin, unusual heartbeat, and dizziness. Some of the other signs of the condition are weakness in muscles, pains and aches, and dyspnea.
Megaloblastic anaemia is a medical condition in which the bone marrow which produce red blood cells produces very large, abnormal, unstructural cells called megaloblasts. This result from disruption in DNA synthesis. It is a nutritional defficiency which is due to inability of the body to absord nutrients. This is caused by deficiency of vitamin B12 and folate. The symptoms include dizziness, increase heart rate, e.t.c
It can be cured by taking dietary supplements of vitamin B12 and folate depending on the root cause.
Determination<span> implies a stable change while the fate of determined cells does not change. </span>Differentiation<span> follows </span>determination<span>, as the cell elaborates a cell-specific developmental program.</span>
