D. The distance between school and your house and the direction you traveled
Answer:
1. transcription of Tau DNA in different directions.
4. different chemical modifications of Tau protein.
Explanation:
Tau gene transcribe in different direction which depends upon the animal age. This happens because at different age and developmental stage, animal produce different RNA binding proteins which leads to formation of alternative splice forms. This reaction is strengthen by the addition of phosphate and sugar molecules which again depending on developmental stage and time.
Proteostasis is mediated by chaperone proteins and protease systems, together with cellular clearance mechanisms such as autophagy and lysosomal degradation.
Chaperone proteins control assembly and inaccurate folding by binding to and stabilizing partly or completely unfolded protein polypeptides till the polypeptide chain is completely synthesized. Chaperone proteins also confirm the stability of unfolded polypeptide chains as they are being translocated into the subcellular organelles.
To learn more about Chaperone proteins here
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