Genetic engineering is the direct manipulation of a specific gene. I would use it in this scenario
Answer:
B. The mutation results in a new, dominant allele
C. The mutation occurs in a gene that controls development and alters differentiation of a cell type during development.
D. The mutation occurs in a codon and alters the function of the final protein
Explanation:
All the above things will change the <u>ultimate expression</u> or phenotype by altering the proteins. Choices B, C, and D will all change the outer functioning.
Choice A only affects the rate of transcription, so it may go faster or slower, but the end product will be the same.
This part that doesn't look like it's one of the choices ("The mutation occurs in a portion of an intron not responsible for exon splicing.") would not affect phenotype, because introns are removed before the RNA is sent out.
Choice E says that the amino acid sequence is unchanged, meaning the protein final product will be the same and the expression will not change.
Answer:
Since, the original DNA sequence has not been provided, the mutation can be an insertion/deletion or a frameshift mutation.
- Mutated DNA
- Frameshift mutation/ insertion or deletion
- All the amino acids changed after the point mutation
Explanation:
Frameshift Mutation:
- A frameshift mutation is the alteration in the reading frame of the DNA due to the addition/deletion of one or two nucleotides.
- This type of mutation moves the mRNA sequence one or two bases forwards or backwards which disrupts the three base codons sequence required for translation into proteins.
- The CT at the end of the sequence is indicative of a frameshift in the DNA reading frame.
- Frameshift mutation affect all amino acids in a polypeptide chain as all codons are moved one or two steps forwards or backwards.
Tight-fitting respirators must seal to the wearer’s face in order to provide expected protection. This includes disposable respirators (also called “filtering facepieces”). Therefore, fit testing is required in the US by the Occupational Safety and Health Administration (OSHA) before a user wears a mandatory respirator on the job, and must be assessed at least annually. In addition, fit tests should be performed:
Whenever a different size, style, model or make of respirator is used.
When any facial changes occur that could affect fit, such as significant weight fluctuation or dental work.
A good fit means the respirator will seal to your skin. A respirator can only work when air passes through the filter. Air will take the path of least resistance, so if the seal isn’t there, the air will go around rather than through the respirator – and therefore lessen the protection.
Safety glasses, hearing protection, face shields, hard hats and coveralls can all vie with a respirator for real estate on a person’s face, head or body. For instance, if a half face respirator doesn’t fit well (especially if it’s too large), it can overlap with glasses. The more that happens, the more fogging can potentially occur on glasses, and the more likely it is that they’ll interfere with the respirator’s seal.
