There are four monoclonal antibodies (MAB) which specifically recognize double-stranded RNA (dsRNA) together with their use in new methods for detecting and characterizing dsRNA in unfractionated nucleic acid extracts. The specificity of the antibodies was analyzed using a panel of 27 different synthetic and naturally occurring nucleic acids. All four antibodies reacted in a highly specific manner with long dsRNA helices, irrespective of their sequence; no binding to single-stranded RNA homopolymers or to DNA or RNA-DNA hybrids were observed.
Monoclonal antibodies
A monoclonal antibody (mAb, more rarely called moAb) is an antibody made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.
Monoclonal antibodies can have monovalent affinity, binding only to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different antibody-secreting plasma cell lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one monoclonal antibody to two epitopes.
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The gradual decline in men's testosterone levels in middle age can reduce their sex drive
A frame-shift mutation would occur. This is because a
deletion will cause a change in codon sequence from the point of mutation to
the end of the mRNA. If the mutation is
closer to the start of the mRNA, the larger the effect of the mutation on the
translated protein.
Answer:
Plaster cast is made up from dry muslin containing starch or dextrose and calcium sulfate.
Explanation:
It is applied to protect and is immobilize an injured bone or joint because it provides rigidity.
It is also used to help the bone and joint from reduce pain that is created during movement.
When plaster becomes wet,it reacts (Between water and calcium sulfate) and produces heat that eventually sets the plaster.It becomes hard when it dries.
The color of plaster casts are smooth and white.
In the absence of competition, P. aurelia grew better than P. caudatum. Every daythere were more P. aurelia than<span>P. caudatum</span>