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4vir4ik [10]
3 years ago
13

In humans, oxygen is effectively delivered to the tissues because of the presence of several allosteric modulators. name three o

f these modulators and explain how their presence allows oxygen to be delivered to the tissues.
Biology
1 answer:
DerKrebs [107]3 years ago
5 0
<span>Els moduladors al·lostèrics que actuen en els humans són el 2,3-Bisfosfoglicerat (2-3-BPG),el CO2 i els H+ . El 2,3-BPG s'uneix al centre del tetrà mer de l'estat T i així l'estabilitzà launió per interaccions iòniques. Els protons actuen perquè quan el pH és baix l'hemoglobinadisminueix la seva afinitat per l'oxigen (efecte Bohr). L'augment de la concentració del CO2 té el mateix efecte perquè el CO2 es combina en H2O i es dissocia en HCO3-i H+ i per aixòdisminueix l'afinitat de l'hemoglobina perquè augmenta la concentració de protons</span>
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