Type-II Diabetes, or non insulin-dependent diabetes mellitus (NIDDM) involves a disrupted insulin signaling mechanism [broken]. There is usually a problem with insulin receptors on cells, and not so much the insulin itself (or pancreas). Sometimes the cause of type-II is referred to as "insulin resistance."
Kinins are always present in an individual's blood. however, in the absence of infection, it is in an inactive form. The kinins are polypeptides that as blood components generate various mediators and many<span> cardinal manifestations of </span>inflammation.
That they are both theories of evolutionary change, but the tempo of the change is different enough that we have the two theories. Rapid evolutionary change punctuated with long periods of stasis describes the former while gradual and incremental change over long periods is the description of the later. Natural selection seems to be more important in gradualism than punctuation, but this is <span>a murky area that is argued about often.</span>