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Vesnalui [34]
4 years ago
15

The most commonly occurring mutation in people with cystic fibrosis is a deletion of a single codon. This results in:__________

Biology
1 answer:
ad-work [718]4 years ago
4 0

Answer:

d) a polypeptide missing an amino acid.

Explanation:

Deletion is a type of mutation when one or more codons from the reading frame are removed. This results in the production of a relatively shorter mRNA that lacks one or more codons otherwise present in the non-mutated mRNA. When there is a deletion of a single codon in the gene for cystic fibrosis, the resultant shorter mRNA codes for a polypeptide chain that does not carry one amino acid. For example, deletion of one codon results in deletion of a Phe  residue present at position 508 in CFTR. The mutated transmembrane protein CFTR folds in an improper way.

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