Parietal<span> cells produce </span><span>hydrochloric acid in response to histamine via H2 receptors, acetylcholine M3 receptors and </span>gastrin<span> receptors. </span>Parietal<span>cells contain an extensive </span>secretory<span> network (called canaliculi) from which the HCl in</span> secreted<span> by an transport into the stomach.</span>