Key factors in mounting an immune response include all of the following except red blood cells.
All exercises require oxygen. The body cannot do anything without oxygen.
Endocrine system regulates hormone production, Estrogen is one of the hormones
Estrogen regulates women's reproductive cycle. Also plays role in keeping bones strong n healthy. After menopause estrogen levels dramatically falls and women experience bone loss and osteoporosis. So, women population affected the greatest.
PS. Women start out life with less bone density then men already.