Thomas Hunt Morgan, who studied fruit flies, provided the first strong confirmation of the chromosome theory. Morgan discovered a mutation that affected fly eye color. ... Based on the inheritance pattern, Morgan concluded that the eye color gene must be located on the X chromosome.
Answer: Combining a basic API with citric acid to produce the citrate salt of the API.
Explanation:
Chemical modifications refers to the processes that involve changes in the general composition of drugs to produce another entity with different chemical properties.
From the answer, Basic API combine with citric acid to produce the citrate salt of API which have different chemical properties from the reactants.
luconeogenesis is a ubiquitous process, present in plants, animals, fungi, bacteria, and other microorganisms.[2] In vertebrates, gluconeogenesis takes place mainly in the liver and, to a lesser extent, in the cortex of the kidneys. In ruminants, this tends to be a continuous process.[3] In many other animals, the process occurs during periods of fasting, starvation, low-carbohydrate diets, or intense exercise. The process is highly endergonic until it is coupled to the hydrolysis of ATP or GTP, effectively making the process exergonic. For example, the pathway leading from pyruvate to glucose-6-phosphate requires 4 molecules of ATP and 2 molecules of GTP to proceed spontaneously. Gluconeogenesis is often associated with ketosis. Gluconeogenesis is also a target of therapy for type 2 diabetes, such as the antidiabetic drug, metformin, which inhibits glucose formation and stimulates glucose uptake by cells.[4] In ruminants, because dietary carbohydrates tend to be metabolized by rumen organisms, gluconeogenesis occurs regardless of fasting, low-carbohydrate diets, exercise, etc.[5]
Gel electrophoresis is a technique used to separate DNA fragments (or other macromolecules, such as RNA and proteins) based on their size and charge. Electrophoresis involves running a current through a gel containing the molecules of interest.
