Answer:
CD40L
Explanation:
The CD40 ligand (CD40L) protein is a transmembrane glycoprotein which is expressed on activated T cells and belongs to the tumor necrosis factor (TNF) superfamily. The hyper IgM syndrome is caused by mutations in the CD40L gene, where the defective protein can no longer bind CD40 on antigen-presenting cells. The X-linked Hyper IgM syndrome is characterized by abnormal levels of immunoglobulins, i.e., low levels of IgG and IgA, and increased/normal levels of IgM. Because CD40L gene is located on the X chromosome, this disorder is observed much more frequently in males than in females.
Answer: Option B.
Explanation:
The first experiment of the passage shows that treatment with TGFBR1 and TGFBR2 antagonists led to lower levels of epithelial cell production. For this conclusion to be strongly valid, we want to show a positive correlation between TGFBR activity and epithelial proliferation.
The answer to the question is C.
Answer:Ovulation—>Fertilization—>Implantation—->Birth
Explanation:the ovum is first released(ovulation) then a sperm merges with it (fertilization) the zygote is moved to the uterus(implantation) it grows to become a baby and the mother delivers it(birth)
