Neurofibromatosis, a genetic disease caused by mutation on the NF1 gene, follows an autosomal dominant pattern of inheritance. T
he diagram shows that the father carries two copies of the defective gene and the mother is unaffected. What percentage of offspring will have neurofibromatosis? Affected: RR Normal: rr
As you can see in a cross shown in the image below, all of the progeny would have the Rr genotype. Since the NF1 gene that is the genetic causes of Neurofibromatosis is expressing <span>an autosomal dominant pattern of inheritance, the heterozygotes would also have the disease. Therefore, the correct answer is D, 100%.</span>