These are all disadvantages but I would say that A and D or A and B are the most serious ones.
First, the electron
transport chain transfer the electrons from electron donors to electron
acceptors using both reduction and oxidation reactions.
Next, the energy
released in these reactions is captured as an electrochemical proton gradient
that triggers the synthesis of ATP synthase and produce adenosine triphosphate
(ATP) from ADP and phosphate group in the process called chemiosmosis.
Lastly, ATP stores
energy chemically in the form of highly strained bonds and together, the
electron transport chain and chemiosmosis makes up the oxidative
phosphorylation which is found in the inner mitochondrial membrane.
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Yes, because vaccines help prevent diseases whereas antibiotics help cure them. (it’s better to prevent)