The primary succession takes a long time to be done. the secondary succesion takes 200-500 years for completion. the secondary succession occurs in an area which has been denuded recently and lately inhabited. soil is present at the beginning of the secondary succession with some organisms. thank you for this question.
Waste would start to build up in the cell since lysosomes have the role of intracellular digestion of waste materials.
A known disease that is caused by a lysosomal malfunction is Hunter's disease