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The correct answer is letter A
Answer:
the concentration of misfolded proteins would be higher than normal.
Explanation:
Chaperones proteins are required for the correct protein folding of proteins. These proteins were first discovered in bacteria. The level of chaperones is increased under thermic stress conditions, it is for that reason that they are also known as heat shock proteins (Hsp). For example, Hsp70 is a chaperon protein constitutively expressed under stress conditions that is involved in the folding of protein precursors and the refolding of misfolded proteins. In humans, Hsp70 is encoded by the HSPA1A gene, and its increased expression level is related to different health problems including neurodegenerative diseases, cerebral ischemia and epilepsy.
