<h2>b) option is correct </h2>
Explanation:
- Some bacterial toxins cause disease by altering the activity of G protein, cholera toxin is one of them
- Cholera toxin catalyse ADP ribosylation of Gs and blocks GTPase activity thus Gs GTP become permanently active
- Constitutive activation of Gs protein continuously induce adenylyl cyclase, cytosolic cAMP level rises that leads to activation of protein kinase A (pKA)
- Activated pKA catalyse phosphorylation of two transmembrane proteins of intestinal epithelial cells:
- CFTR cause excessive outflow of Cl- ion and Na+ H+ exchange cause efflux of Na+ ion, both enters in gut and form Na+ Cl-
- Na+Cl- leads to outflow of water from the gut, resulting in diarrhea and dehydration and this condition may cause death of organisms due to loss of water and ions
The correct answer is: Binding of the neurotransmitter causes chemically gated sodium channels to open in the motor end plate (junctional folds of the sarcolemma) and sodium enters the cell.
Action potential travels through the membrane of the presynaptic cell causing the voltage-gated channels permeable to calcium ions to open. Ca2+ flow through the presynaptic membrane and increase the Ca concentration in the cell which will activate proteins attached to vesicles that contain a neurotransmitter (e.g. acetylcholine). Vesicles fuse with the membrane of the presynaptic cell, thereby release their contents into the synaptic cleft-space between the membranes of the pre- and postsynaptic cells. Neurotransmitter ACh binds to its receptors on the postsynaptic membrane and its binding causes depolarization of the target cell (muscle cell). Depolarization occurs because sodium enters the cell as a result of neurotransmitter receptor binding.
I think the correct answer from the choices listed above is option A. For metamorphism to occur, the parent rock must be in solid form. Metamorphism is the alteration of the structure of a rock by factors like heat and temperature so it must be the material should be in solid form.
When converted to a household measurement, 9 kilograms is approximately equal to a
