Cells are made up smaller units called organelles that undertake various critical roles in the activities of the cell. Some of these organelles include, mitochondria whose major function is formation and production of energy in the form of ATP, Ribosome is an organelle involved in the protein synthesis, lysosome is involved in the destruction of old and worn out tissues and organelles, Golgi apparatus or complex helps in transportation, modification and packaging of secretions such as proteins and lipids. Therefore, alcoholism affects the activity of lysosomes in the liver since they are tasked in the digestion of proteins using hydrolytic enzymes.
sickle cell anemia is caused by a mutation in the hemoglobin beta (or HBB) gene and it leads to a single change in amino acid sequence. this gene is located on chromosome 19
My guess would be H₂O/ water, since osmosis is a form of passive transport and I can't see the model the question references. Gases like O₂/ oxygen, CO₂/ carbon dioxide, and simple sugars like glucose can also pass through a cell membrane with passive transport though.
