Answer:
France ceded all territory east of the Mississippi to the British Empire, following the English victory in the Seven Years' War. The rest of Louisiana passed into Spanish hands after the Treaty of Paris of 1763. From that year until the beginning of the 19th century, the vast territory of approximately 2 million square kilometers west of the Mississippi River became part of the Spanish Empire.
In 1755, during the Spanish domination, several thousands of Francophones from the Acadia region (now Nova Scotia, New Brunswick and Prince Edward Island, in Canada) took refuge in Louisiana, after being expelled by the English invaders of the eastern coasts of the territory that is now Canada, establishing these refugees in the southwest region of Spanish Louisiana called Acadiana. The Spaniards, who wanted more Catholic population, welcomed the refugees. The Cajunes are their current descendants. In addition, immigrants from the Canary Islands arrived between 1778 and 1783.
In 1800, Napoleonic France acquired Louisiana back from Spain through the Treaty of San Ildefonso, until it was sold to the United States in 1803.