Answer is b: FALSE.
Tolerance refers to the body's responses to the functional effects of the chemical ethanol in alcoholic beverages. This includes the recovery from the effects, and the resistance to certain symptoms.
Answer:
The goal of public health is to improve health outcomes for populations through the achievement of the objectives of preventing disease and the health consequences of environmental hazards and natural or man-made disasters; promoting behaviors that reduce the risk of communicable and non-communicable diseases
Explanation:
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Answer:
1 answer
Explanation:
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Answer and Explanation:
Ergotamine has been used for over 50 years and was the first specific drug to treat migraine attacks. Its therapeutic effect is due in part to its ability to contract the vessels. It is a vasoconstricting alkaloid used in migraine attacks, when treatment with non-steroidal anti-inflammatory drugs has no effect.
The mechanism of action of ergotamine is complex. The molecule has structural similarities to neurotransmitters such as seratonin, dopamine and adrenaline, and can therefore bind to various receptors and function as an inhibitor. Its use in the treatment of migraines is due to its vasoconstrictor effect of extracerebral intracranial blood vessels through their binding to the 5-HT1B receptor and inhibition of neurotransmitter binding.
Overuse of ergotamine may cause nausea, vomiting (to direct effects on the Central Nervous System in the vomiting centers) , malaise, headache, constriction of peripheral vessels and more severe effects such as ischemia of the extremities.
Ergotamine poisoning is called ergotism.
Ergotamine should not be used in patients with peripheral arterial or venous vascular insufficiency, ischemic heart disease, cerebrovascular disease, systemic infection and hypertension without effective control.
