The introduction of European diseases to American Indians was an accident that no one expected. Neither the colonists nor the Indians had a good understanding of why this affected the Native people so badly.
The great impact of disease on the Native population of America is an important part of the story of European exploration. Experts believe that as much as 90 percent of the American Indian population may have died from illnesses introduced to America by Europeans. This means that only one in ten Natives survived this hidden enemy. Their descendants are the 2.5 million Indians who live in the United States today.
New trade goods represented another big change that European explorers and colonists brought to American Indians. Soon after meeting their European visitors, Indians became very interested in things that the colonists could provide. In a short time, the Indians began using these new materials and products in their everyday lives. Native hunters were eager to trade prepared deer hides and other pelts for lengths of colored cloth. Metal tools such as axes and knives became valuable new resources. Soon American Indian men put aside their bows and arrows for European firearms, powder, and lead shot.
Another big change connected to this new trade was slavery. Europeans needed workers to help build houses and clear fields. They soon realized that they could offer trade goods like tools and weapons to certain American Indian tribes that would bring them other Indians captured in tribal wars. These captured Indians were bought and sold as slaves.