Answer:
Yes, there is no convincing scientific evidence that thimerosal causes harm by the low doses of thimerosal in vaccines, except for minor reactions like redness and swelling at the injection site
Explanation:
Thimerosal has been used safely as a vaccine additive, added to some vaccines to prevent germs like bacteria and fungi from growing in them dated since early 1930s. Though, Thimerosal contains mercury but the type of mercury doesn’t stays in the body, and is unlikely to make human fall sick.
Most people doesn't have any allergic reaction to it except for redness and swelling at the injection site as early mentioned and this is considered irrelevant when compared to effect of vaccine when contaminated by germ which could cause serious illness or death.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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Mountain lions/highest trophic levels receives less energy as energy is lost at each level/mountain lions are larger than most animals and require (smaller) individuals for food.
I believe the answer to this question is cellular respiration
Maybe bro. You should try and give it a chance most likely they’ll say yes :)
