Answer: 1. extremely cold temperatures.
Answer:
What impact does a decrease in pH have on urchins?
Decrease in pH simply means high degree of acidity which affects every living organism. The impact of high acidity affects there food intake, development of their young ones (juvenile)
Explanation:

<em><u>Nitrogen</u></em><em><u> </u></em><em><u>is</u></em><em><u> </u></em><em><u>not</u></em><em><u> </u></em><em><u>a</u></em><em><u> </u></em><em><u>product</u></em><em><u> </u></em><em><u>of</u></em><em><u> </u></em><em><u>photosynthesis</u></em>
<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
</span>
Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>