Answer:
Polypeptides are composed of amino acids, and we know amino acids are differently charged, have different R groups, and also have different isoelectric points. Depending on different isoelectric points and charged groups, the polypeptides can be separated and because a protein has its lowest solubility on its isoelectric point.
So in this question,
(a) (Lys-Ala)3 ; this is highly positively charged (polar) at pH 7 than (Gly)20 which is uncharged except for the amino and carboxyl terminal.
(b) (Glu)20 ; it is highly negatively charged at pH 7 whereas (Phe-Met)3 is much less polar and hence less soluble.
(c) (Asn-Ser-His)5 ; at pH 3, because in (Ala-Asp-Gly)5 the carboxylate groups of Asp residues are partially protonated and neutral, whereas in (Asn-Ser-His)5 , the imidazole groups of His residues are fully protonated and positively charged.
(d) (Asn-Ser-His)5; at pH 6.0; both polymers have polar Ser sidechains, but (Asn-Ser-His)5 also has the polar Asn side chains and partially protonated His side chains.
Explanation:
I believe its B i hope that helps
"editorial blogs are considered an unreliable source because the author may not have a science background".
Answer: Transducting the signal from an activated receptor to the next protein in the pathway.
Explanation:
G-proteins are a family of proteins whose main function is to carry a signal from a receptor on the cell membrane to one or more target proteins. So, G-proteins are very important in signal transduction. They depend on the nucleotide guanosine triphosphate (GTP) for activation.
They are the third largest family of proteins in eukaryotic cells and hundreds have been described. G-proteins are involved in signal transduction in many different ways, which is why there are so many different types of these proteins. <u>They can be involved in signalling the activation or silencing of DNA translation, in the reception of hormonal and neuronal signals, etc.</u> They are characterized by their interaction with guanosine triphosphate (GTP) leading to hydrolysis of the nucleotide to guanosine diphosphate (GDP). In this way, a stimulus from outside the cell, a ligand for example, accesses the cell's receptor associated with G-protein or GPCR, triggering a cascade of enzymatic activities or second messengers in response. Therefore, GTPase activity is crucial for their functioning as biological switches.
G-protein-coupled receptors (GPCR) comprise the targets of several biogenic amines, eicosanoids, and other molecules that send signals to target cells such as lipids, hormonal peptides, opiates, amino acids (GABA), and many other protein peptides and ligands. Effectors that are regulated by G-protein include enzymes such as adenyl cyclase, phospholipase C, phosphodiesterases and plasma membrane ion channels selective for Ca²+ and K+.
Also, because of their number and physiological importance, GPCRs are widely used targets for drugs.
Oh gosh gosh oh yeah lol oh yeah sweetie no I’m gonna be