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2 years ago

The appearance of a novel phenotype resulting from the substitution of a single base pair might be due to

Biology

1 answer:

Gelneren [198K]2 years ago

3 0

Answer:

There are several answers to this question: The appearance of a novel phenotype resulting from a substitution of a single base pair might be due to:___. These possibilities are:

1. A change in the sequence of amino acids. It must be remembered that proteins are the ones that carry out the instructions present in genes, therefore, a change in the sequence may show also a change in a base pair, and a change in what is expressed phenotypically.

2. Change in the amount of protein that is transcribed. Again proteins are the ones that carry out the instructions from genetic material. A change in DNA will show in how not just amino acids will be arranged, but also the structure, and amount of protein transcribed, and also the types. This will alter the phenotypical expression.

3. Change in the developmental time and/or location at which a gene is expressed. Time and also the placement of the base pairs in the genetic sequence can alter how these are expressed when they are translated into RNA.

4. Alteration in a gene that codes for a non-translated RNA. It is RNA the one that will transfer information from genes in DNA and the final product, which are proteins. However, when DNA has a change in the genes that will be translated into RNA, the process may not be carried out, and if RNA is not produced, then neither will proteins. The absence of a specific sequence in RNA will also affect the production of protein and thus a phenotypical expression may, or may not, happen.

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PLEASE HELP ME!!

Minchanka [31]

Answer:

Evolution

Explanation:

Evolution is a gradual change in a population that occurs overtime in a species.

6 0

2 years ago

the couple is also concerned about their child inheriting hemophilia, another rare disease, which is x-linked. natalie’s brother

IgorC [24]

Hemophilia is a recessive X-linked condition and is inherited from parents. . The probability that Natalie and Daniel’s first child has hemophilia is 1/4, not 1/8. The statement is false.

<h3>What is an X-linked gene?</h3>

When talking about sex-linked genes, we refer to all those genes located in one of the sex-chromosomes and not in the somatic ones.

X-linked genes are the genes located specifically in the X sex chromosome.

Traits coded by these genes are inherited. This is, X-linked genes are transmitted from parents to children through generations.

According to this, X-linked genetic disorders will be inherited as well.

Men have a high probability of being affected since they only have one copy of the X chromosome.

In women, the effect of the mutation might be musk in heterozygous state if the mutation is recessive.

Hemophilia is a recessive X-linked disorder, which means it is coded by the recessive allele.

X+ ⇒ X chrosomosome with Dominant allele

X- ⇒ X chrosomosome with Recessive allele

Genotype Phenotype

X+X+ Healthy woman

X+X- Healthy carrier woman

X-X- Hemophilic woman

X+Y Healthy man

X-Y Hemophilic man

Let us make a pedigree of these families,

Natalie's family:

Mother healthy carrier X+X-

Father healthy X+Y

Brother hemophilic X-Y

Natalie Healthy X+X- or X+X+

Natalie has 1/2 chances of being carrier X+X- and 1/2 of being X+X+.

Daniel's family:

Mother healthy carrier X+X-

Father hemophilic X-Y

Sister hemophilic X-X-

Daniel Healthy X+Y

He has 1/2 chances of being healthy X+Y and 1/2 of being affected X-Y.

According to the product probability rule, if events A and B are independent from each other, the probability of occurrence of both events together is

P(A∩B) = P(A) x P(B)

In this case,