Question

The classic "beads-on-a-string" structure is the most decondensed chromatin structure possible and is produced experimentally. Which chromatin components are not retained when this structure is generated?A. 30-nm fiber
B. linker DNA
C. nucleosome core particles
D. core histones
E. linker histones

Answer 1

Answer:

linker DNA

Explanation:

the classic beads on a string structure is termed as the nucleosome; which is the most basic level of chromosome packaging. the nucleosome is made up of 2 molecules each of the four histone proteins (H2A, H2B, H3, H4) to form an octamer around which a length of DNA is wrapped. linkage of this nucleosome to another nucleosome is done by a length of linker DNA and a linker histone (H1). thus experimentally to produce this structure, the linker DNA between two nucleosomes is degraded by nucleases to extract the structure. thus the linker DNA is not retained after the experiment.