Answer:
The correct answer is - option A
Explanation:
Phosphoinositide 3-kinases or PI-3 kinse, are enzymes involved in essential cellular functions such as the growth of the cell, proliferation, motility, differentiation, survival and intracellular movement, which in turn are plays role in cancer.
PI3-kinase with oncogene PIK3CA and tumor suppressor PTEN, is implicated in the insensitivity of cancer tumors.
Thus, the correct answer is option A)
Answer:
by the sarcoplasmic reticulum's calcium ion pumps
Explanation:
Rigor mortis or postmortem rigidity, is a state caused by chemical changes in the muscles that occur post mortem and cause the limbs of the corpse to stiffen.
This occurs because after death, there is no cellular respiration and consequently, no oxygen nor ATP (ATP is required for the muscle relaxation).
Calcium enters the cytosol after death because it is released due to the deterioration of the sarcoplasmic reticulum and due to the breakdown of the sarcolemma. Ca2+ ions activate the formation of actin-myosin cross-bridging necessary for the contraction. Muscles are unable to relax, because myosin heads continue to bind with the active sites of actin and there is no ATP to destabilize the myosin-actin bond.
Answer:
B) Viruses are killing some of his B cells and becoming incorporated into the genomes of others.
Explanation:
Epstein-Barr virus causes infectious mononucleosis by following mechanism.
1) Epstein-Barr virus attaches to and infects epithelium of the throat where it replicates and causes pharyngitis.
2) Virions enter the lymphoid vessels and are carried to the lymph nodes. Some virions escape the lymphnode trap and are carried to the bloodstream.
3) Virions attach specifically to B lymphocytes and infect them, producing either latent infection or productive infection.
4)The infected B lymphocytes actively replicate and differentiate into cells producing random immunoglobulins.
5)T cells respond to infection and destroy the lymphocytes replicating EBV vitus.
6) Latently infected B lymphocytes become immortal. They are not attacked by T cells.
C) slate, a metamorphic rock